Contribution of resident and circulating precursors to tumor-infiltrating CD8 + T cell populations in lung cancer

Paul Gueguen , Christina Metoikidou (1) , Thomas Dupic (2) , Myriam Lawand (1) , Christel Goudot (1) , Sylvain Baulande (3) , Sonia Lameiras (4) , Olivier Lantz (1) , Nicolas Girard (5) , Agathe Seguin-Givelet (4, 6) , Marine Lefevre (7) , Thierry Mora (8) , Aleksandra Walczak (8) , Joshua Waterfall (9) , Sebastian Amigorena (4)

1 U932 - Immunité et cancer
2 OEB - Department of Organismic and Evolutionary Biology [Cambridge]
3 Centre de recherche de l'Institut Curie [Paris]
4 Institut Curie [Paris]
5 UVSQ Santé - Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil
6 CIMI - Centre d'Immunologie et des Maladies Infectieuses
7 IMM - Institut Mutualiste de Montsouris
8 Physique Statistique et Inférence pour la Biologie
9 LPTENS - Laboratoire de Physique Théorique de l'ENS [École Normale Supérieure]

CD8 + T cells in lung tumors differentiate through convergent pathways to an expanded and actively cycling terminal state.

Domains: Life Sciences [q-bio]

Paul Gueguen, Christina Metoikidou, Thomas Dupic, Myriam Lawand, Christel Goudot, et al.. Contribution of resident and circulating precursors to tumor-infiltrating CD8 + T cell populations in lung cancer. Science Immunology, 2021, 6 (55), ⟨10.1126/sciimmunol.abd5778⟩. ⟨hal-03877456⟩