Beneficial short-term effect of autogenic drainage on peripheral resistance in childhood cystic fibrosis disease - Archive ouverte HAL Access content directly
Journal Articles BMC Pulmonary Medicine Year : 2022

Beneficial short-term effect of autogenic drainage on peripheral resistance in childhood cystic fibrosis disease

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Plamen Bokov
  • Function : Author
Michèle Gerardin
  • Function : Author
Géraldine Brialix
  • Function : Author
Emmanuelle da Costa Noble
  • Function : Author
Romain Juif
  • Function : Author
Antonia Vital Foucher
  • Function : Author
Laurence Le Clainche
  • Function : Author
Véronique Houdouin
  • Function : Author
Benjamin Mauroy
Christophe Delclaux
  • Function : Author

Abstract

Abstract Background Airway clearance techniques are supposed to be a necessary adjunct for the enhancement of impaired peripheral clearance in cystic fibrosis (CF). The objective was to assess the effect of one physiotherapy session (autogenic drainage: AD) on mucus clearance (sputum wet weight) and impulse oscillometry system (IOS) indices, including those obtained from extended Resistance-Inertance-Compliance (eRIC) modelling, considering the degree of bronchial congestion. Methods Thirty children with CF (median age: 12.7 years) in a stable condition prospectively underwent IOS measurements at baseline and after AD. They were divided in two groups: with (visual analog scale of bronchial congestion by the physiotherapist ≥ 5/10) and without (scale < 5/10) bronchial congestion. Paired-comparison of the effects of AD on airway resistance measurements was done with Wilcoxon test. Results The congestion scale correlated with the wet weight of sputum production during the session (Pearson test: p < 0.0001, R = 0.66). Ten children had bronchial congestion and 20 were without congestion. In the whole group, R5–20 Hz significantly decreased after AD ( P = 0.049), which was related to a decrease in the children with congestion ( P = 0.025), whereas it was not significantly modified in the children without congestion ( P = 0.327). The eRIC model allowed the calculation of the peripheral resistance of the respiratory system, which also decreased in the children with congestion ( P = 0.037), however, not modified in the children without congestion ( P = 0.390). Conclusion One session of autogenic drainage has the ability to decrease peripheral resistance obtained from IOS measurements, more specifically in children with CF with moderate to severe bronchial congestion. Trial registration ClinicalTrials.gov Identifier: NCT04094441.

Dates and versions

hal-03871631 , version 1 (25-11-2022)

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Plamen Bokov, Michèle Gerardin, Géraldine Brialix, Emmanuelle da Costa Noble, Romain Juif, et al.. Beneficial short-term effect of autogenic drainage on peripheral resistance in childhood cystic fibrosis disease. BMC Pulmonary Medicine, 2022, 22 (1), pp.241. ⟨10.1186/s12890-022-02039-2⟩. ⟨hal-03871631⟩
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