Loss of human LGR4/GPR48 causes a novel syndromic form of severe neonatal saltwasting due to disrupted WNT signaling altering adrenal zonation

Cécily Lucas (1) , Kay-Sara Sauter , Michael Steigert , Delphine Mallet , James Wilmouth (1) , Julie Olabe (1) , Ingrid Plotton , Yves Morel , Daniel Aeberli , Franca Wagner , Hans Clevers , Amit V Pandey , Pierre Val (1) , Florence Roucher-Boulez (1) , Christa E Flück

1 GReD - Génétique, Reproduction et Développement

Domains: Life Sciences [q-bio]

Cécily Lucas, Kay-Sara Sauter, Michael Steigert, Delphine Mallet, James Wilmouth, et al.. Loss of human LGR4/GPR48 causes a novel syndromic form of severe neonatal saltwasting due to disrupted WNT signaling altering adrenal zonation. Journal of Clinical Investigation, In press. ⟨hal-03868988⟩