Echocardiographic evidence of left ventricular untwisting-filling interplay - CNRS - Centre national de la recherche scientifique Accéder directement au contenu
Article Dans Une Revue Cardiovascular Ultrasound Année : 2020

Echocardiographic evidence of left ventricular untwisting-filling interplay

Résumé

Abstract Background Left ventricular untwisting generates an early diastolic intraventricular pressure gradient (DIVPG) than can be quantified by echocardiography. We sought to confirm the quantitative relationship between peak untwisting rate and peak DIVPG in a large adult population. Methods From our echocardiographic database, we retrieved all the echocardiograms with a normal left ventricular ejection fraction, for whom color Doppler M-Mode interrogation of mitral inflow was available, and left ventricular untwisting rate was measurable using speckle tracking. Standard indices of left ventricular early diastolic function were assessed by Doppler (peaks E, e’ and Vp) and speckle tracking (peak strain rate Esr). Load dependency of DIVPG and untwisting rate was evaluated using a passive leg raising maneuver. Results We included 154 subjects, aged between 18 to 77 years old, 63% were male. Test-retest reliability for color Doppler-derived DIVPG measurements was good, the intraclass correlation coefficients were 0.97 [0.91–0.99] and 0.97 [0.67–0.99] for intra- and inter-observer reproducibility, respectively. Peak DIVPG was positively correlated with peak untwisting rate (r = 0.73, P < 0.001). On multivariate analysis, peak DIVPG was the only diastolic parameter that was independently associated with untwisting rate. Age and gender were the clinical predictive factors for peak untwisting rate, whereas only age was independently associated with peak DIVPG. Untwisting rate and DIVPG were both load-dependent, without affecting their relationship. Conclusions Color Doppler-derived peak DIVPG was quantitatively and independently associated with peak untwisting rate. It thus provides a reliable flow-based index of early left ventricular diastolic function.
Fichier principal
Vignette du fichier
s12947-020-00190-6.pdf (3.13 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-03538698 , version 1 (12-09-2022)

Identifiants

Citer

Amir Hodzic, Damien Garcia, Eric Saloux, Paula Ribeiro, Amélie Ethier, et al.. Echocardiographic evidence of left ventricular untwisting-filling interplay. Cardiovascular Ultrasound, 2020, 18 (1), pp.8. ⟨10.1186/s12947-020-00190-6⟩. ⟨hal-03538698⟩
112 Consultations
20 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More