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Articulating the “stem cell niche” paradigm through the lens of non-model aquatic invertebrates

Abstract : Abstract Stem cells (SCs) in vertebrates typically reside in “stem cell niches” (SCNs), morphologically restricted tissue microenvironments that are important for SC survival and proliferation. SCNs are broadly defined by properties including physical location, but in contrast to vertebrates and other “model” organisms, aquatic invertebrate SCs do not have clearly documented niche outlines or properties. Life strategies such as regeneration or asexual reproduction may have conditioned the niche architectural variability in aquatic or marine animal groups. By both establishing the invertebrates SCNs as independent types, yet allowing inclusiveness among them, the comparative analysis will allow the future functional characterization of SCNs.
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https://hal-cnrs.archives-ouvertes.fr/hal-03538388
Contributor : Alexander Ereskovskiy Connect in order to contact the contributor
Submitted on : Friday, April 1, 2022 - 6:19:28 PM
Last modification on : Friday, May 6, 2022 - 3:46:38 AM

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P. Martinez, L. Ballarin, Alexander Ereskovsky, E. Gazave, B. Hobmayer, et al.. Articulating the “stem cell niche” paradigm through the lens of non-model aquatic invertebrates. BMC Biology, BioMed Central, 2022, 20 (1), pp.23. ⟨10.1186/s12915-022-01230-5⟩. ⟨hal-03538388⟩

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