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Syndromes de sevrage des nouveau-nés de mères toxicomanes substituées par la méthadone ou la buprénorphine haut dosage ; Etude multicentrique de 246 cas

Abstract : Perinatal prognosis of pregnant drug abusers is better with intensive prenatal care and substitution maintenance programs. There is a large body of data in the literature on methadone (MTD), but very little on high-dose buprenorphine (HDB). The objective of this study was to compare 2 groups of pregnant women maintained on MTD or HDB for perinatal events. Study design. - Prospective multicentric study; all neonates (NN) whose mothers has been maintained during pregnancy on MTD or HDB were included by 34 French perinatal centers with specialized staff for care of these pregnant drug abusers. Results. - Two hundred and forty-six pregnant women were included: 93 (38%) MTD and 153 (62%) HDB. Social and perinatal data, prenatal care and factors correlated with poor prenatal care are reported. Forty-six percent of the pregnant women had good prenatal care; 88% had peridural analgesia; mean birthweight=2838g; mean gestational age=38.7 weeks; prematurity
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https://hal-cnrs.archives-ouvertes.fr/hal-03476861
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Submitted on : Monday, December 13, 2021 - 11:19:00 AM
Last modification on : Wednesday, December 15, 2021 - 1:43:28 PM

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  • HAL Id : hal-03476861, version 1

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C Lejeune, S Aubisson, Laurence Simmat-Durand, F Cneude, M Piquet, et al.. Syndromes de sevrage des nouveau-nés de mères toxicomanes substituées par la méthadone ou la buprénorphine haut dosage ; Etude multicentrique de 246 cas. Annales de Medecine Interne, Masson Editeur, 2001, 152 (7), pp.2S21-2S27. ⟨hal-03476861⟩

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