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Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study

Marc-Emmanuel Dumas 1, 2, 3 Thomas Drake 4 Aya Riad Cameron Fairfield Conor Egan Stephen Knight Riinu Pius Hayley Hardwick Lisa Norman Catherine Shaw Kenneth Mclean Aa Roger Thompson Antonia Ho Olivia Swann Michael Sullivan Felipe Soares Karl Holden Laura Merson Daniel Plotkin Louise Sigfrid Thushan de Silva Michelle Girvan Clare Jackson Clark Russell Jake Dunning Tom Solomon Gail Carson Piero Olliaro Jonathan Nguyen-Van-Tam Lance Turtle Annemarie Docherty Peter Jm Openshaw J Kenneth Baillie Ewen Harrison Malcolm Semple Beatrice Alex Benjamin Bach Wendy Barclay Debby Bogaert Meera Chand Graham Cooke Ana da Silva Filipe Tom Fletcher Christopher Green Julian Hiscox Antonia Yw Ho Peter Horby Samreen Ijaz Say Khoo Paul Klenerman Andrew Law Wei Shen Lim Alexander Mentzer Alison Meynert Mahdad Noursadeghi Shona Moore Massimo Palmarini William Paxton Georgios Pollakis Nicholas Price Andrew Rambaut David Robertson Vanessa Sancho-Shimizu Janet Scott Shiranee Sriskandan David Stuart Charlotte Summers Richard Tedder Emma Thomson Ryan Thwaites Lance Cw Turtle Rishi Gupta Carlo Palmieri Maria Zambon Julian Griffin Zoltan Takats Kanta Chechi Petros Andrikopoulos Anthonia Osagie Michael Olanipekun Sonia Liggi Matthew Lewis Gonçalo dos Santos Correia Caroline Sands Panteleimon Takis Lynn Maslen Chloe Donohue Fiona Griffiths Wilna Oosthuyzen Derek Murphy Jo Dalton Egle Saviciute Stephanie Roberts Janet Harrison Laura Marsh Marie Connor Sophie Halpin Carrol Gamble James Lee Gary Leeming Murray Wham Sara Clohisey Ross Hendry James Scott-Brown William Greenhalf Victoria Shaw Sarah Mcdonald Seán Keating Katie Ahmed Jane Armstrong Milton Ashworth Innocent Asiimwe Siddharth Bakshi Samantha Barlow Laura Booth Benjamin Brennan Katie Bullock Benjamin Wa Catterall Jordan Clark Emily Clarke Sarah Cole Louise Cooper Helen Cox Christopher Davis Oslem Dincarslan Chris Dunn Philip Dyer Angela Elliott Anthony Evans Lorna Finch Lewis Ws Fisher Terry Foster Isabel Garcia-Dorival Philip Gunning Catherine Hartley Rebecca Jensen Christopher Jones Trevor Jones Shadia Khandaker Katharine King Robyn Kiy Chrysa Koukorava Annette Lake Suzannah Lant Diane Latawiec Lara Lavelle-Langham Daniella Lefteri Lauren Lett Lucia Livoti Maria Mancini Laurence Mcevoy John Mclauchlan Soeren Metelmann Nahida Miah Joanna Middleton Joyce Mitchell Ellen Murphy Rebekah Penrice-Randal Jack Pilgrim Tessa Prince Will Reynolds P. Matthew Ridley Debby Sales Rebecca Shears Benjamin Small Krishanthi Subramaniam Agnieska Szemiel Aislynn Taggart Jolanta Tanianis-Hughes Jordan Thomas Erwan Trochu Libby van Tonder Eve Wilcock J. Eunice Zhang Lisa Flaherty Nicole Maziere Emily Cass Alejandra Doce Carracedo Nicola Carlucci Anthony Holmes Hannah Massey Lee Murphy Nicola Wrobel Sarah Mccafferty Kirstie Morrice Alan Maclean Kayode Adeniji Daniel Agranoff Ken Agwuh Dhiraj Ail Erin Aldera Ana Alegria Brian Angus Abdul Ashish Dougal Atkinson Shahedal Bari Gavin Barlow Stella Barnass Nicholas Barrett Christopher Bassford Sneha Basude David Baxter Michael Beadsworth Jolanta Bernatoniene John Berridge Nicola Best Pieter Bothma David Chadwick Robin Brittain-Long Naomi Bulteel Tom Burden Andrew Burtenshaw Vikki Caruth Duncan Chambler Nigel Chee Jenny Child Srikanth Chukkambotla Tom Clark Paul Collini Catherine Cosgrove Jason Cupitt Maria-Teresa Cutino-Moguel Paul Dark Chris Dawson Samir Dervisevic Phil Donnison Sam Douthwaite Andrew Drummond Ingrid Durand Ahilanadan Dushianthan Tristan Dyer Cariad Evans Chi Eziefula Chrisopher Fegan Adam Finn Duncan Fullerton Sanjeev Garg Atul Garg Effrossyni Gkrania-Klotsas Jo Godden Arthur Goldsmith Clive Graham Elaine Hardy Stuart Hartshorn Daniel Harvey Peter Havalda Daniel Hawcutt Maria Hobrok Luke Hodgson Anil Hormis Michael Jacobs Susan Jain Paul Jennings Agilan Kaliappan Vidya Kasipandian Stephen Kegg Michael Kelsey Jason Kendall Caroline Kerrison Ian Kerslake Oliver Koch Gouri Koduri George Koshy Shondipon Laha Steven Laird Susan Larkin Tamas Leiner Patrick Lillie James Limb Vanessa Linnett Jeff Little Mark Lyttle Michael Macmahon Emily Macnaughton Ravish Mankregod Huw Masson Elijah Matovu Katherine Mccullough Ruth Mcewen Manjula Meda Gary Mills Jane Minton Mariyam Mirfenderesky Kavya Mohandas Quen Mok James Moon Elinoor Moore Patrick Morgan Craig Morris Katherine Mortimore Samuel Moses Mbiye Mpenge Rohinton Mulla Michael Murphy Megan Nagel Thapas Nagarajan Mark Nelson Lillian Norris Matthew O'Shea Igor Otahal Marlies Ostermann Mark Pais Selva Panchatsharam Danai Papakonstantinou Hassan Paraiso Brij Patel Natalie Pattison Justin Pepperell Mark Peters Mandeep Phull Stefania Pintus Jagtur Singh Pooni Frank Post David Price Rachel Prout Nikolas Rae Henrik Reschreiter Tim Reynolds Neil Richardson Mark Roberts Devender Roberts Alistair Rose Guy Rousseau Brendan Ryan Taranprit Saluja Aarti Shah Prad Shanmuga Anil Sharma Anna Shawcross Jeremy Sizer Manu Shankar-Hari Richard Smith Catherine Snelson Nick Spittle Nikki Staines Tom Stambach Richard Stewart Pradeep Subudhi Tamas Szakmany Kate Tatham Jo Thomas Chris Thompson Robert Thompson Ascanio Tridente Darell Tupper-Carey Mary Twagira Nick Vallotton Rama Vancheeswaran Lisa Vincent-Smith Shico Visuvanathan Alan Vuylsteke Sam Waddy Rachel Wake Andrew Walden Ingeborg Welters Tony Whitehouse Paul Whittaker Ashley Whittington Padmasayee Papineni Meme Wijesinghe Martin Williams Lawrence Wilson Sarah Sarah Stephen Winchester Martin Wiselka Adam Wolverson Daniel Wootton Andrew Workman Bryan Yates Peter Young
Abstract : COVID-19 is a multisystem disease and patients who survive might have in-hospital complications. These complications are likely to have important short-term and long-term consequences for patients, health-care utilisation, health-care system preparedness, and society amidst the ongoing COVID-19 pandemic. Our aim was to characterise the extent and effect of COVID-19 complications, particularly in those who survive, using the International Severe Acute Respiratory and Emerging Infections Consortium WHO Clinical Characterisation Protocol UK.
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https://hal-cnrs.archives-ouvertes.fr/hal-03451256
Contributor : Marc-Emmanuel Dumas Connect in order to contact the contributor
Submitted on : Friday, November 26, 2021 - 1:12:17 PM
Last modification on : Wednesday, January 19, 2022 - 12:48:06 PM

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Marc-Emmanuel Dumas, Thomas Drake, Aya Riad, Cameron Fairfield, Conor Egan, et al.. Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study. The Lancet, Elsevier, 2021, 398 (10296), pp.223-237. ⟨10.1016/S0140-6736(21)00799-6⟩. ⟨hal-03451256⟩

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