Protein-primed RNA synthesis in SARS-CoVs and structural basis for inhibition by AT-527

Ashleigh Shannon; Véronique Fattorini; Bhawna Sama; Barbara Selisko; Mikael Feracci; Camille Falcou; Pierre Gauffre; Priscila El Kazzi; Etienne Decroly; Nadia Rabah; Karine Alvarez; Cécilia Eydoux; Jean-Claude Guillemot; Françoise Debart; J.J. Vasseur; Mathieu Noel; Adel Moussa; Steven Good; Kai Lin; Jean-Pierre Sommadossi; yingxiao Zhu; Xiaodong yan; Hui Shi; François Ferron; Bruno Canard

doi:10.1101/2021.03.23.436564

Preprints, Working Papers, ...

Protein-primed RNA synthesis in SARS-CoVs and structural basis for inhibition by AT-527

Ashleigh Shannon ¹ Véronique Fattorini ¹ Bhawna Sama ¹ Barbara Selisko ¹ Mikael Feracci ¹ Camille Falcou Pierre Gauffre Priscila El Kazzi Etienne Decroly ¹ Nadia Rabah ¹ Karine Alvarez ¹ Cécilia Eydoux Jean-Claude Guillemot Françoise Debart ² J.J. Vasseur ² Mathieu Noel ² Adel Moussa Steven Good Kai Lin Jean-Pierre Sommadossi yingxiao Zhu Xiaodong yan Hui Shi François Ferron ¹ Bruno Canard ¹

1 AFMB - Architecture et fonction des macromolécules biologiques

2 IBMM - Institut des Biomolécules Max Mousseron [Pôle Chimie Balard]

Document type :

Preprints, Working Papers, ...

Domain :

Chemical Sciences / Analytical chemistry

Chemical Sciences / Medicinal Chemistry

Chemical Sciences / Organic chemistry

Chemical Sciences

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https://hal-cnrs.archives-ouvertes.fr/hal-03367971
Contributor : Jean-Jacques Vasseur Connect in order to contact the contributor
Submitted on : Wednesday, October 6, 2021 - 3:06:37 PM
Last modification on : Saturday, May 7, 2022 - 3:38:39 AM
Long-term archiving on: : Friday, January 7, 2022 - 7:08:52 PM

Protein-primed RNA synthesis in SARS-CoVs and structural basis for inhibition by AT-527

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Protein-primed RNA synthesis in SARS-CoVs and structural basis for inhibition by AT-527

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