Human enteric glial cells are defective for 15-HETE production and epithelial permeability control in Crohn’s disease

Camille Pochard (1) , Sabrina Coquenlorge , Julie Jaulin , Nicolas Cenac , Nathalie Vergnolle , Guillaume Meurette , Marie Freyssinet , Michel Neunlist , Malvyne Rolli-Derkinderen (1, 2)

1 TENS - The Enteric Nervous System in gut and brain disorders [U1235]
2 IMAD - Institut des maladies de l'appareil digestif [Nantes]

Transcript Profiling No Writing Assistance No Author Contributions MRD and MN designed the research study, supervised the study and wrote the paper. CP, SC, JJ and NC performed experiments. MRD and CP analyzed the data. NC and NV participated in the critical reading of the manuscript. GM managed and provided human surgical samples.

Keywords: Enteric Nervous System; Inflammatory Bowel Disease; AMPK; ZO-1

Domains: Life Sciences [q-bio]

Camille Pochard, Sabrina Coquenlorge, Julie Jaulin, Nicolas Cenac, Nathalie Vergnolle, et al.. Human enteric glial cells are defective for 15-HETE production and epithelial permeability control in Crohn’s disease. Gastroenterology, 2016, 150 (1), pp.168-180. ⟨10.1053/j.gastro.2015.09.038⟩. ⟨hal-03153620⟩