Defects in 15-HETE Production and Control of Epithelial Permeability by Human Enteric Glial Cells From Patients With Crohn's Disease

Camille Pochard (1) , Sabrina Coquenlorge (1) , Julie Jaulin (1) , Nicolas Cenac (2) , Nathalie Vergnolle (2) , Guillaume Meurette (1, 3) , Marie Freyssinet (1) , Michel Neunlist (1) , Malvyne Rolli-Derkinderen (1, 4)

1 TENS - The Enteric Nervous System in gut and brain disorders [U1235]
2 CPTP - Centre de Physiopathologie Toulouse Purpan
3 CHU Nantes - Centre Hospitalier Universitaire de Nantes
4 IMAD - Institut des maladies de l'appareil digestif [Nantes]

Transcript Profiling No Writing Assistance No Author Contributions MRD and MN designed the research study, supervised the study and wrote the paper. CP, SC, JJ and NC performed experiments. MRD and CP analyzed the data. NC and NV participated in the critical reading of the manuscript. GM managed and provided human surgical samples.

Mots clés: Enteric Nervous System; Inflammatory Bowel Disease; AMPK; ZO-1

Domaines: Sciences du Vivant [q-bio]

Camille Pochard, Sabrina Coquenlorge, Julie Jaulin, Nicolas Cenac, Nathalie Vergnolle, et al.. Defects in 15-HETE Production and Control of Epithelial Permeability by Human Enteric Glial Cells From Patients With Crohn's Disease. Gastroenterology, 2016, 150 (1), pp.168-180. ⟨10.1053/j.gastro.2015.09.038⟩. ⟨hal-03153620⟩