Drosophila Tubulin-Specific Chaperone E Recruits Tubulin around Chromatin to Promote Mitotic Spindle Assembly

Mathieu Métivier (1) , Emmanuel Gallaud (1) , Alexandre Thomas , Aude Pascal (1) , Jean-Philippe Gagné (2) , Guy G. Poirier (3) , Denis Chrétien (1) , Romain Gibeaux (1) , Laurent Richard-Parpaillon (1) , Christelle Benaud (1) , Régis Giet (1)

1 IGDR - Institut de Génétique et Développement de Rennes
2 CHU de Québec–Université Laval
3 ULaval - Université Laval [Québec]

Keywords: CAP-Gly motif; Drosophila; Ran; microtubule nucleation; mitosis; mitotic spindle assembly; neural stem cells; nuclear pore proteins; tubulin dynamics; tubulin-specific chaperone E; CAP-Gly motif

Domains: Life Sciences [q-bio]; Cellular Biology; Subcellular Processes [q-bio.SC]; Life Sciences [q-bio]; Genetics; Animal genetics; Life Sciences [q-bio]; Cancer; Life Sciences [q-bio]; Development Biology; Embryology and Organogenesis; Life Sciences [q-bio]; Biochemistry, Molecular Biology; Biochemistry [q-bio.BM]

Mathieu Métivier, Emmanuel Gallaud, Alexandre Thomas, Aude Pascal, Jean-Philippe Gagné, et al.. Drosophila Tubulin-Specific Chaperone E Recruits Tubulin around Chromatin to Promote Mitotic Spindle Assembly. Current Biology - CB, 2021, 31 (4), pp.684-695.e6. ⟨10.1016/j.cub.2020.11.009⟩. ⟨hal-03100180⟩