Ageing enhances the shedding of splenocyte microvesicles with endothelial pro-senescent effect that is prevented by a short-term intake of omega-3 PUFA EPA:DHA 6:1

Abdul Wahid Qureshi (1) , Raed Adill Hannon Altamimy (1) , Ali El Habhab (1) , Hanine El Itawi (1) , Muhammad Akmal Farooq (1) , Fatiha Zobairi (1) , Hira Hasan (1) , Lamia Amoura (1) , Mohamad Kassem (1) , Cyril Auger (1) , Valérie B. Schini-Kerth (1) , Florence Toti (1)

1 NanoRegMed - Nanomédecine Régénérative

Ageing enhances the shedding of splenocyte microvesicles with endothelial pro-senescent effect that is prevented by a short-term intake of omega-3 PUFA EPA:DHA 6:1,

Keywords: Microparticles; endothelial senescence; spleen leukocyte; oxidative stress; angiotensin system; omega-3 polyunsaturated fatty acids

Domains: Life Sciences [q-bio]; Pharmaceutical sciences; Pharmacology; Life Sciences [q-bio]; Human health and pathology; Cardiology and cardiovascular system

Abdul Wahid Qureshi, Raed Adill Hannon Altamimy, Ali El Habhab, Hanine El Itawi, Muhammad Akmal Farooq, et al.. Ageing enhances the shedding of splenocyte microvesicles with endothelial pro-senescent effect that is prevented by a short-term intake of omega-3 PUFA EPA:DHA 6:1. Biochemical Pharmacology, 2020, 173, pp.113734. ⟨10.1016/j.bcp.2019.113734⟩. ⟨hal-03057570⟩