Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells

Fanny Chalmin; Sylvain Ladoire; Grégoire Mignot; Julie Vincent; Mélanie Bruchard; Jean-Paul Remy-Martin; Wilfrid Boireau; Alain Rouleau; Benoit Simon; David Lanneau; Aurélie de Thonel; Gabriele Multhoff; Arlette Hamman; François Martin; Bruno Chauffert; Eric Solary; Laurence Zitvogel; Carmen Garrido; Bernhard Ryffel; Christophe Borg; Lionel Apetoh; Cédric Rébé; François Ghiringhelli

doi:10.1172/JCI40483

Journal articles

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells

Fanny Chalmin Sylvain Ladoire Grégoire Mignot Julie Vincent Mélanie Bruchard Jean-Paul Remy-Martin Wilfrid Boireau Alain Rouleau Benoit Simon David Lanneau Aurélie de Thonel ¹ Gabriele Multhoff Arlette Hamman François Martin Bruno Chauffert Eric Solary Laurence Zitvogel Carmen Garrido Bernhard Ryffel Christophe Borg Lionel Apetoh Cédric Rébé François Ghiringhelli

1 EDC (UMR_7216) - Centre épigénétique et destin cellulaire

Fanny Chalmin
Author

Sylvain Ladoire
Author

Grégoire Mignot
Author

Julie Vincent
Author
PersonId : 762168IdRef : 156378604

Mélanie Bruchard
Author

Jean-Paul Remy-Martin
Author

Wilfrid Boireau
Author
PersonId : 739086
IdHAL : wilfrid-boireauORCID : 0000-0002-5667-8254

Alain Rouleau
Author

Benoit Simon
Author

David Lanneau
Author

Aurélie de Thonel ¹
Author

Gabriele Multhoff
Author

Arlette Hamman
Author

François Martin
Author

Bruno Chauffert
Author
PersonId : 919116
ORCID : 0000-0001-7533-5401IdRef : 067133428

Eric Solary
Author
PersonId : 757151
ORCID : 0000-0002-8629-1341IdRef : 050500031

Laurence Zitvogel
Author
PersonId : 756204ORCID : 0000-0003-1596-0998IdRef : 083439587

Carmen Garrido
Author

Bernhard Ryffel
Author
PersonId : 841831

Christophe Borg
Author

Lionel Apetoh
Author

Cédric Rébé
Author

François Ghiringhelli
Author
PersonId : 756197ORCID : 0000-0002-5465-8305

1 EDC (UMR_7216) - Centre épigénétique et destin cellulaire (Université Paris Diderot Bât. Lamarck case postale 7042 75205 Paris CEDEX 13 - France) StructId : 1004995

CNRS - Centre National de la Recherche Scientifique : UMR_7216 (France) StructId : 441569
UPCité - Université Paris Cité : UMR_7216 (85 boulevard Saint-Germain 75006 Paris - France) StructId : 557826

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Journal articles

Domain :

Life Sciences [q-bio]

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https://hal-cnrs.archives-ouvertes.fr/hal-03030322
Contributor : Mathieu Manquant Connect in order to contact the contributor
Submitted on : Monday, November 30, 2020 - 8:31:34 AM
Last modification on : Friday, August 5, 2022 - 12:00:06 PM

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HAL Id : hal-03030322, version 1
DOI : 10.1172/JCI40483
PUBMEDCENTRAL : PMC2810085

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CNRS | UNIV-PARIS | UP-SCIENCES

Citation

Fanny Chalmin, Sylvain Ladoire, Grégoire Mignot, Julie Vincent, Mélanie Bruchard, et al.. Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells. Journal of Clinical Investigation, American Society for Clinical Investigation, 2020, ⟨10.1172/JCI40483⟩. ⟨hal-03030322⟩

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells

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Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells

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