HAL CNRS portal

Journal articles

Genomic analysis of European Drosophila melanogaster populations reveals longitudinal structure, continent-wide selection, and previously unknown DNA viruses

Martin Kapun ¹ Maite G Barrón ² Fabian Staubach ³ Darren J Obbard ⁴ R Axel W. Wiberg ^{5, 6} Jorge Vieira ⁷ Clément Goubert ⁸ Omar Rota-Stabelli ⁹ Maaria Kankare ¹⁰ María Bogaerts-Márquez ² Annabelle A. Haudry ⁸ Lena Waidele ³ Iryna Kozeretska ¹¹ Elena G Pasyukov ¹² Volker Loeschcke ¹³ Marta Pascual ¹⁴ Cristina P Vieira ^{15, 16, 17, 8} Svitlana Serga ¹¹ Catherine Montchamp-Moreau ¹⁸ Jessica Abbott ¹⁹ Patricia Gibert ^{20, 8} Damiano Porcelli ²¹ Nico Posnien ²² Alejandro Sánchez-Gracia ¹⁴ Sonja Grath ²³ Élio Sucena ²⁴ Alan O Bergland ²⁵ Maria Pilar Garcia Guerreiro ²⁶ Banu Sebnem Onder ²⁷ Eliza Argyridou ²³ Lain Guio ² Fristrup Schou ¹⁹ Bart Deplancke ²⁸ Cristina Vieira ⁸ Michael G Ritchie ⁵ Bas J Zwaan ²⁹ Eran Tauber ³⁰ Dorcas J Orengo ¹⁴ Eva Puerma ¹⁴ Montserrat Aguadé ¹⁴ Paul S Schmidt ³¹ John Parsch ²³ Andrea J Betancourt ³² Thomas Flatt ³³ Josefa González ²

1 University of Fribourg

2 UPF - Universitat Pompeu Fabra [Barcelona]

3 University of Freiburg [Freiburg]

4 University of Edinburgh

5 University of St Andrews [Scotland]

6 Unibas - University of Basel

7 IBMC - Instituto de Biologia Molecular e Celular - institute for molecular and cell biology [Porto, Portugal]

8 LBBE - Laboratoire de Biométrie et Biologie Evolutive - UMR 5558

9 Fondazione Edmund Mach [San Michele all'Adige]

10 JYU - University of Jyväskylä

11 UKMA - National University of Kyiv-Mohyla Academy

12 Institute of Molecular Genetics of National Research Centre «Kurchatov Institute» [Moscow, Russia]

13 Aarhus University [Aarhus]

14 UB - Universitat de Barcelona

15 Eléments transposables, évolution, populations

GINSENG - Département génétique, interactions et évolution des génomes [LBBE]

16 GINSENG - Département génétique, interactions et évolution des génomes [LBBE]

17 ERABLE - Equipe de recherche européenne en algorithmique et biologie formelle et expérimentale

Inria Grenoble - Rhône-Alpes

18 EGCE - Evolution, génomes, comportement et écologie

19 Lund University [Lund]

20 Génétique et évolution des interactions hôtes-parasites

GINSENG - Département génétique, interactions et évolution des génomes [LBBE]

21 Department of Animal and Plant Sciences [Sheffield]

22 University of Göttingen - Georg-August-Universität Göttingen

23 LMU - Ludwig-Maximilians-Universität München

24 IGC - Instituto Gulbenkian de Ciência [Oeiras]

25 University of Virginia [Charlottesville]

26 UAB - Universitat Autònoma de Barcelona

27 Hacettepe University = Hacettepe Üniversitesi

28 School of Life Sciences [Lausanne]

29 WUR - Wageningen University and Research [Wageningen]

30 University of Haifa [Haifa]

31 University of Pennsylvania [Philadelphia]

32 University of Liverpool

33 UNIL - University of Lausanne

Abstract : Genetic variation is the fuel of evolution, with standing genetic variation especially important for short-term evolution and local adaptation. To date, studies of spatiotemporal patterns of genetic variation in natural populations have been challenging, as comprehensive sampling is logistically difficult, and sequencing of entire populations costly. Here, we address these issues using a collaborative approach, sequencing 48 pooled population samples from 32 locations, and perform the first continent-wide genomic analysis of genetic variation in European Drosophila melanogaster. Our analyses uncover longitudinal population structure, provide evidence for continent-wide selective sweeps, identify candidate genes for local climate adaptation, and document clines in chromosomal inversion and transposable element frequencies. We also characterize variation among populations in the composition of the fly microbiome, and identify five new DNA viruses in our samples.

Document type :

Journal articles

Domain :

Environmental Sciences / Biodiversity and Ecology

Life Sciences [q-bio] / Biodiversity / Populations and Evolution [q-bio.PE]

Life Sciences [q-bio] / Genetics / Populations and Evolution [q-bio.PE]

Life Sciences [q-bio] / Ecology, environment / Symbiosis

Complete list of metadata

Cited literature [105 references] Display Hide Download

https://hal-cnrs.archives-ouvertes.fr/hal-03014405
Contributor : Patricia GIBERT Connect in order to contact the contributor
Submitted on : Thursday, November 19, 2020 - 6:05:10 PM
Last modification on : Saturday, July 9, 2022 - 4:02:09 AM
Long-term archiving on: : Saturday, February 20, 2021 - 7:21:35 PM