Abstract : We review recent experimental work combining circular dichroism spectroscopy and T-jump experiment to investigate elementary dynamics in the folding/unfolding of biomolecules. A nanosecond setup is presented for poly(Glutamic acid) studies whereas a millisecond one is developed for investigation of DNA G-quadruplex dynamics.
https://hal-cnrs.archives-ouvertes.fr/hal-03003923 Contributor : François HacheConnect in order to contact the contributor Submitted on : Wednesday, November 18, 2020 - 4:45:04 PM Last modification on : Thursday, November 18, 2021 - 3:42:02 PM Long-term archiving on: : Friday, February 19, 2021 - 8:21:20 PM
Pascale Changenet, François Hache. T-jump and circular dichroism: folding dynamics in proteins and DNA. Molecular Crystals and Liquid Crystals, Taylor & Francis, 2019, 693 (1), pp.49-56. ⟨10.1080/15421406.2020.1723918⟩. ⟨hal-03003923⟩