Mitochondrial DNA Stimulates TLR9-Dependent Neutrophil Extracellular Trap Formation in Primary Graft Dysfunction

Beñat Mallavia (1) , Fengchun Liu , Emma Lefrançais (2) , Simon Cleary , Nicholas Kwaan , Jennifer Tian , Melia Magnen , David Sayah , Allison Soong , Joy Chen , Rajan Saggar , Michael Shino , David Ross , Ariss Derhovanessian , Joseph Lynch , Abbas Ardehali , S. Sam Weigt , John Belperio , Steven Hays , Jeffrey Golden , Lorriana Leard , Rupal Shah , Mary Ellen Kleinhenz , Aida Venado , Jasleen Kukreja , Jonathan Singer , Mark Looney

1 UCSF - Department of Medicine, Microbiology and Immunology
2 IPBS - Institut de pharmacologie et de biologie structurale

Domains: Life Sciences [q-bio]; Human health and pathology; Pulmonology and respiratory tract; Life Sciences [q-bio]; Immunology; Innate immunity; Life Sciences [q-bio]; Life Sciences [q-bio]; Biochemistry, Molecular Biology; Life Sciences [q-bio]; Cellular Biology; Cell Behavior [q-bio.CB]; Life Sciences [q-bio]; Human health and pathology; Tissues and Organs [q-bio.TO]

Beñat Mallavia, Fengchun Liu, Emma Lefrançais, Simon Cleary, Nicholas Kwaan, et al.. Mitochondrial DNA Stimulates TLR9-Dependent Neutrophil Extracellular Trap Formation in Primary Graft Dysfunction. American Journal of Respiratory Cell and Molecular Biology, 2020, 62 (3), pp.364-372. ⟨10.1165/rcmb.2019-0140OC⟩. ⟨hal-02997951⟩