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Book Sections Year : 2000

14-3-3 proteins and growth control

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Abstract

The 14-3-3 proteins constitute a family that is highly conserved in a wide range of organisms, including higher eukaryotes, invertebrates and plants. Variants of 14-3-3 proteins assembled in homo- and heterodimers were found to interact with diverse cellular proteins. Until recently, the biological role of 14-3-3 members was still poorly understood. However, the results of an increasing number of studies on their structure and function are converging to define 14-3-3 proteins as a novel type of adaptor that modulates interactions between components involved in signal transduction pathway and in cell cycle control.
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hal-02353433 , version 1 (07-11-2019)

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Véronique Baldin. 14-3-3 proteins and growth control. Progress in Cell Cycle Research, 4, Springer US, pp.49-60, 2000, ⟨10.1007/978-1-4615-4253-7_5⟩. ⟨hal-02353433⟩
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