A coupled model for the dynamics of gas exchanges in the human lung with Haldane and Bohr's effects - Archive ouverte HAL Access content directly
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A coupled model for the dynamics of gas exchanges in the human lung with Haldane and Bohr's effects

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Abstract

We propose an integrated dynamical model for oxygen and carbon dioxide transfer from the lung into the blood, coupled with a lumped mechanical model for the ventilation process, for healthy patients as well as in pathological cases. In particular, we focus on the Bohr and Haldane effects, which induce a nonlinear coupling between the oxygen and the carbon dioxide. We also take into account the dead space volume, which requires a special attention in the pathological cases.
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Dates and versions

hal-03883301 , version 1 (03-12-2022)

Identifiers

  • HAL Id : hal-03883301 , version 1

Cite

Laurent Boudin, Céline Grandmont, Bérénice Grec, Sébastien Martin. A coupled model for the dynamics of gas exchanges in the human lung with Haldane and Bohr's effects. 2022. ⟨hal-03883301⟩
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