Enantioselective Au( i )-catalyzed dearomatization of 1-naphthols with allenamides through Tethered Counterion-Directed Catalysis - Laboratoire de Chimie Théorique Accéder directement au contenu
Article Dans Une Revue Chemical Communications Année : 2021

Enantioselective Au( i )-catalyzed dearomatization of 1-naphthols with allenamides through Tethered Counterion-Directed Catalysis

Résumé

The Tethered Counterion-Directed Catalysis (TCDC) approach has been applied to the enantioselective Au(I) catalyzed dearomatizations of 1-naphthols with allenamides. Stereocontrol is ensured by the intramolecular ion-pairing between the chiral gold-tethered phosphate and an iminium unit, that provides a rigid, well-defined chiral environment to the key electrophilic intermediate.

Domaines

Chimie
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Dates et versions

hal-03405405 , version 1 (05-09-2022)

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Citer

Yunliang Yu, Zhenhao Zhang, Arnaud Voituriez, Nicolas Rabasso, Gilles Frison, et al.. Enantioselective Au( i )-catalyzed dearomatization of 1-naphthols with allenamides through Tethered Counterion-Directed Catalysis. Chemical Communications, 2021, 57 (82), pp.10779-10782. ⟨10.1039/D1CC04088J⟩. ⟨hal-03405405⟩
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