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Detection of SARS‐CoV‐2 in two cats during the second wave of the COVID‐19 pandemic in France

Abstract : Although there are several reports in the literature of SARS-CoV-2 infection in cats, few SARS-CoV-2 sequences from infected cats have been published. In this study, SARS-CoV-2 infection was evaluated in two cats by clinical observation, molecular biology (qPCR and NGS), and serology (microsphere immunoassay and seroneutralization). Following the observation of symptomatic SARS-CoV-2 infection in two cats, infection status was confirmed by RT-qPCR and, in one cat, serological analysis for antibodies against N-protein and S-protein, as well as neutralizing antibodies. Comparative analysis of five SARS-CoV-2 sequence fragments obtained from one of the cats showed that this infection was not with one of the three recently emerged variants of SARS-CoV-2. This study provides additional information on the clinical, molecular, and serological aspects of SARS-CoV-2 infection in cats.
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Submitted on : Friday, October 29, 2021 - 12:21:31 PM
Last modification on : Friday, August 5, 2022 - 10:43:00 AM
Long-term archiving on: : Monday, January 31, 2022 - 9:38:19 AM

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Matthieu Fritz, Nicolas Nesi, Solène Denolly, Bertrand Boson, Vincent Legros, et al.. Detection of SARS‐CoV‐2 in two cats during the second wave of the COVID‐19 pandemic in France. Veterinary Medicine and Science, Wiley, 2021, pp.Online Version of Record before inclusion in an issue. ⟨10.1002/vms3.638⟩. ⟨hal-03408737⟩

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